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NICE guidance update on the management of Crohn’s disease

For Crohn's disease

The National Institute for Health and Care Excellence (NICE) have updated their guidance on the management of Crohn's disease.

Crohn’s disease is a lifelong condition that causes inflammation in parts of the digestive system (most commonly in the small intestine). It can cause symptoms like diarrhoea, abdominal pain, tiredness and weight loss. Symptoms usually come and go – they may flare up before easing off again for a few weeks or months. There is no cure for Crohn’s disease, so the aim of treatment is to get good control over symptoms to help people have the best quality of life they can.

The guideline is designed to make a difference to people with Crohn’s disease by making sure:
  • doctors know which drug treatments work best to treat flare ups, and how to prevent future flare-ups
  • your doctor explains the pros and cons of different drug treatments, including any side effects, so you can decide what’s right for you
  • your doctor involves you in decisions about how to manage your condition between flare-ups.


You can follow developments in Crohn's disease by using our Condition Tracker service which provides users with updates about the conditions and medicines they are interested in.

The guidance also covers how patients and healthcare professionals can make decisions together.

Decisions about treatment and care are best when they are made together. Your healthcare professionals should give you clear information, talk with you about your options and listen carefully to your views and concerns.

To help you make decisions, think about:
  • what matters most to you – what do you want to get out of any treatments?
  • what are you most worried about – are there risks or downsides to the treatments that worry you more than others?
  • how will the condition and its treatment affect your day to day life?
  • what happens if you don’t want to have treatment?
If you can’t understand the information you are given, tell your healthcare professional.

Authored on 12/05/19
Links available in full article

© NICE [2019]

Crohn’s disease: management. NICE guideline [NG129]. Published date: May 2019
Available from: See Link below. All rights reserved. Subject to Notice of rights
NICE guidance is prepared for the National Health Service in England. All NICE guidance is subject to regular review and may be updated or withdrawn. NICE accepts no responsibility for the use of its content in this product/publication.

The information provided by NICE was accurate at the time this article was issued.


NICE guidance on the management of Crohn's disease

Reporting of suspected adverse reactions

Reporting suspected adverse reactions (side effects) after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals or patients are asked to report any suspected adverse reactions via the Yellow Card Scheme at yellowcard.mhra.gov.uk or search for MHRA Yellow Card in the Google Play or Apple App Store.


Disclaimer: This site is designed to offer information for general educational purposes only. The health information furnished on this site and the interactive responses are not intended to be professional advice and are not intended to replace personal consultation with a qualified physician, pharmacist, or other healthcare professional. We cannot provide individual medical advice. You must always seek the advice of a professional for questions related to a disease, disease symptoms, and appropriate therapeutic treatments.


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