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New migraine treatment fremanezumab (Ajovy▼) approved for use in EU

Ajovy▼, for Migraine from Teva UK Limited

The European Medicines Agency (EMA) have approved Teva's migraine treatment, fremanezumab (brand name Ajovy▼) for use in the EU.

The EMA stated that Ajovy can reduce the number of days patients have moderate to severe headaches and migraines. As most of the side effects are manageable and mild or moderate in severity, the European Medicines Agency decided that Ajovy’s benefits are greater than its risks and it can be authorised for use in the EU.

You can follow developments with Ajovy by using our Medicines Tracker service which provides users with updates about the medicines they are interested in.

About migraine (source NHS)
A migraine is usually a moderate or severe headache felt as a throbbing pain on 1 side of the head.

Many people also have symptoms such as feeling sick, being sick and increased sensitivity to light or sound.

Migraine is a common health condition, affecting around 1 in every 5 women and around 1 in every 15 men. They usually begin in early adulthood.

There are several types of migraine, including:
  • migraine with aura – where there are specific warning signs just before the migraine begins, such as seeing flashing lights
  • migraine without aura – the most common type, where the migraine happens without the specific warning signs
  • migraine aura without headache, also known as silent migraine – where an aura or other migraine symptoms are experienced, but a headache does not develop
Some people have migraines frequently, up to several times a week. Other people only have a migraine occasionally.

It's possible for years to pass between migraine attacks.

About Ajovy (source EMA)
Ajovy is a medicine used to prevent migraine in adults who have migraines at least 4 days a month. The active substance contained in Ajovy is fremanezumab.

A chemical messenger called CGRP contributes to the development of migraine. Ajovy is a monoclonal antibody (a type of protein) designed to attach to CGRP and prevent it from binding to its target on the body’s cells thereby helping to prevent migraines from occurring.

Ajovy was first made available in the EU in 2019. It is manufactured by Teva.

Sources
European Medicines Agency website page for Ajovy
NHS website for migraine
Contains public sector information licensed under the Open Government Licence v3.0.
Accessed 24/07/19
Links available in full article

EMA information on Ajovy

New medicines and vaccines that are under additional monitoring have an inverted black triangle symbol (▼) displayed in their package leaflet and summary of product characteristics, together with a short sentence explaining what the triangle means – it does not mean the medicine is unsafe. You should report all suspected adverse drug reactions (ADRs) for these products. ADRs can be reported by your doctor, pharmacist or online via the Yellow Card system.

Reporting of suspected adverse reactions

Reporting suspected adverse reactions (side effects) after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals or patients are asked to report any suspected adverse reactions via the Yellow Card Scheme at yellowcard.mhra.gov.uk or search for MHRA Yellow Card in the Google Play or Apple App Store.


Disclaimer: This site is designed to offer information for general educational purposes only. The health information furnished on this site and the interactive responses are not intended to be professional advice and are not intended to replace personal consultation with a qualified physician, pharmacist, or other healthcare professional. We cannot provide individual medical advice. You must always seek the advice of a professional for questions related to a disease, disease symptoms, and appropriate therapeutic treatments.


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